Introduction Solitary osseous plasmacytoma rarely involves the distal extremities. We report a case and provide a brief review of the relevant literature.

Case presentation We report a 64-year-old man who presented with swelling, mild pain and a deformed right index finger. The workup led to the diagnosis of solitary osseous plasmacytoma and the patient eventually required amputation of his finger. With clinical follow-up, the disease spread to regional lymph nodes and subsequently the patient developed systemic involvement and received chemotherapy.

Conclusions Solitary osseous plasmacytoma should be considered in the differential diagnosis of distal extremity neoplasms.