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A template for a clinico-pathological audit of medical liver biopsies
  1. Richard Colling1,
  2. Eve Fryer1,
  3. Jeremy Cobbold2,
  4. Jane Collier2,
  5. Elena Collantes1,
  6. Lai Mun Wang1,
  7. Stefan Hubscher3,
  8. Judith Wyatt4,
  9. Kenneth Fleming5
  1. 1Department of Cellular Pathology, Oxford University Hospitals NHS Trust, John Radcliffe Hospital, Oxford, UK
  2. 2Department of Gastroenterology, Oxford University Hospitals NHS Trust, Oxford, UK
  3. 3School of Cancer Sciences, University of Birmingham, Birmingham, UK
  4. 4Department of Histopathology, St. James's Hospital, Leeds, UK
  5. 5Medical Sciences Division, University of Oxford, Oxford, UK
  1. Correspondence to Dr Richard Colling, Department of Cellular Pathology, Oxford University Hospitals NHS Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK; rtcolling{at}


Aims With changing indications for performing medical liver biopsies, we aimed to develop a tool to allow pathologists to evaluate the current usefulness, value and impact of their medical liver biopsy service.

Methods We designed and piloted a questionnaire-based clinico-pathological audit for medical liver biopsies.

Results The audit tool was simple to implement and provided useful information about our service. Hepatologists felt that 96% of reports were clinically useful. 56% of biopsies confirmed clinical diagnoses, 46% helped differentiate between diagnoses and 42% were able to exclude possible diagnoses. 74% resulted in a change of management and 27% of liver biopsies resulted in a diagnosis which was not clinically suspected.

Conclusions We demonstrate the usefulness of an audit tool in providing evidence of the value of the liver pathology service in a large UK regional centre.


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