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Antiphospholipid syndrome presenting as cerebral venous sinus thrombosis: a case series and a review
  1. Abdul Shlebak
  1. Correspondence to Dr Abdul Shlebak, Department of Haematology, Haemostasis and Thrombosis Section, Imperial College Healthcare NHS Trust Hospitals, St Mary's Hospital Campus, Praed St, London W2 1NY, UK; a.shlebak{at}


The cerebral venous sinus system is a rare site for venous thrombosis except in patients with antiphospholipid syndrome. We describe three patients presenting with cerebral venous thrombosis in association with other thrombotic sites in two patients and as an only site in one patient. Antiphospholipid syndrome has varied clinical manifestations but the defining feature is the persistent presence of antiphospholipid antibodies. In this report we will review the clinical and laboratory diagnostic criteria and the management of patients with antiphospholipid syndrome.


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