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A rare and unusual cause of mammographic calcification in the breast
  1. Andrew Robinson1,
  2. Abeer M Shaaban2
  1. 1 Department of Musculoskeletal Pathology, Royal Orthopaedic Hospital, Birmingham, UK
  2. 2 Department of Cellular Pathology, Queen Elizabeth Hospital Birmingham, Birmingham, UK
  1. Correspondence to Dr Abeer M Shaaban, Department of Cellular Pathology, Queen Elizabeth Hospital and University of Birmingham, B15 2GW, Birmingham, UK; a.shaaban{at}


Clinical question A 45-year-old woman is found, on family history screening, to have calcification within the upper outer quadrant of her right breast. A diagnostic mammotome biopsy was performed. Review the interactive digital slide and consider your diagnosis and appropriate management.

What is your diagnosis?

  1. Collagenous spherulosis

  2. Flat epithelial atypia with psammomatous calcification

  3. Liesegang rings with lactational changes

  4. Parasitic infection

  5. Spheroid type amyloid


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  • Handling editor Iskander Chaudhry

  • Contributors AR and AS diagnosed the lesion, searched the literature and contributed to the writing up. Both authors approved the final manuscript.

  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.

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  • Correction
    BMJ Publishing Group Ltd and Association of Clinical Pathologists