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Breast tumour resembling tall cell variant of papillary thyroid carcinoma: case presentation (in a patient with Lynch syndrome)
  1. Luis Gai1,
  2. Susan J Done2,
  3. Donald Cook1,
  4. Nash Denic1,
  5. Polycarp Erivwo1,
  6. Kim Voisey1,
  7. Kenneth Kao1,3
  1. 1 Division of Anatomical Pathology, Laboratory Medicine Program, Eastern Health, St John’s, Newfoundland and Labrador, Canada
  2. 2 Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada
  3. 3 Division of Biomedical Science, Faculty of Medicine, Memorial University, St John’s, Newfoundland and Labrador, Canada
  1. Correspondence to Dr Luis Gai, Division of Anatomical Pathology, Laboratory Medicine Program, Eastern Health, St John’s, NL A1B 3V6, Canada; luis.gai{at}

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A breast tumour resembling the tall cell variant of a papillary thyroid carcinoma (BTPTC) was first reported in 2003 by Eusebi and colleagues.1 It was described as a breast carcinoma with histological features similar to the tall cell variant of a papillary thyroid carcinoma. These breast tumours are generally considered of indolent behaviour. There are however not enough data to predict prognosis in these rare variants of breast cancer. Since the original description of BTPTC in 2003, only a handful of additional reports of the same type of lesion have been described.2–5 These cases can be challenging, and the first differential diagnosis to take into consideration is a metastatic papillary thyroid carcinoma.

Here, we report a case of a BTPTC in a 55-year-old patient with Lynch syndrome (LS) who presented with asymmetric density within her right medial upper breast on a routine mammogram. Spot …

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  • Handling editor Runjan Chetty.

  • Contributors LG and SJD provided the diagnosis, with assistance from DC, PE and ND. KK and KV performed the laboratory investigation. LG and KK prepared and SJD edited the manuscript.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.