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Review of pathological findings in laparoscopic sleeve gastrectomy specimens performed for morbid obesity
  1. Klaudia Nowak1,
  2. Adam DiPalma2,
  3. Stefano Serra1,
  4. Fayez Quereshy2,
  5. Timothy Jackson2,
  6. Allan Okrainec2,
  7. Runjan Chetty1
  1. 1 Department of Pathology, University Health Network Laboratory Medicine Program, University of Toronto, Toronto, Ontario, Canada
  2. 2 Department of General Surgery, University Health Network and University of Toronto, Toronto, Ontario, Canada
  1. Correspondence to Professor Runjan Chetty, Department of Pathology, University Health Network Laboratory Medicine Program, University of Toronto, Toronto, Canada; runjan.chetty{at}


Background Bariatric surgical procedures are employed when there is a failure of lifestyle modification in arresting obesity. Laparoscopic sleeve gastrectomy (LSG) is quickly becoming the bariatric surgical procedure of choice. LSG results in a gastric remnant that is subject to pathological examination. The objective of this paper is to review the literature in regard to histological findings identified in gastric remnants post-LSG and identify the most pertinent histological findings.

Materials and methods A literature search was performed to identify relevant case series. Data gathered from relevant case series then underwent statistical analysis.

Results The most common histological findings in an LSG specimen were clinically indolent findings such as no pathological abnormalities identified followed by non-specific gastritis. A minority of cases demonstrated clinically actionable findings for which Helicobacter pylori represented the majority of these findings.

Conclusion There is a broad spectrum of pathological findings in LSG specimens, ranging from clinically indolent to clinically actionable. The most common histological findings are clinically indolent and only a small portion are of clinical significance and, hence, actionable.

  • gastrointestinal disease
  • helicobacter pylori
  • gastric pathology

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  • Handling editor Tahir S Pillay.

  • Contributors All authors contributed to this manuscript. KN and RC conceived the idea and all authors contributed to the design and writing of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Ethics approval Institutional REB ethics approval was obtained: CAPCR-ID: 17-5578.

  • Provenance and peer review Not commissioned; externally peer reviewed.