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Virtual case of the month
Relapsing-remitting painful masses of the skeletal muscle
  1. Gaetano Vattemi,
  2. Valeria Guglielmi,
  3. Matteo Marini,
  4. Giuliano Tomelleri
  1. Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology, University of Verona, Verona, Italy
  1. Correspondence to Dr Gaetano Vattemi, Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Neurology, University of Verona, Verona 37134, Italy; gaetano.vattemi{at}univr.it

http://dx.doi.org/10.1136/jclinpath-2019-206090

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    Clinical question

    A 59-year-old male patient complained, from age 36, of insidious appearance in several weeks of a circumscribed painful mass, single or multiple, under the skin with hard consistency on palpation. At first, these masses were localised on sural aspect of the legs, thereafter on arms, thighs and, occasionally, on trunk and face. They had a diameter ranging from 3 cm to 5 cm and the overlying skin tissue was normal. Pain might increase with movement causing functional limitation of the corresponding limb. In the first years, they spontaneously remitted within 2–3 months, successively in 6–7 months. Onset of these lesions was never preceded or accompanied by systemic symptoms such as fever, weakness and fatigue. A muscle biopsy was taken …

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    Footnotes

    • Handling editor Iskander Chaudhry.

    • Correction notice This article has been corrected since it appeared Online First. The link to the digital slide has been added.

    • Contributors All authors fulfil the criteria of authorship because of their substantial contribution to analysis, interpretation or manuscript preparation and have read and approved the submission of the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Disclaimer The manuscript has not been published and is not being considered for publication elsewhere.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Commissioned; internally peer reviewed.