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Rare and unusual spindle cell tumour
  1. Harumi Nakamura1,
  2. Masanori Kitamura1,
  3. Hiroko Murata2,
  4. Shuhei Kida3,
  5. Jun Ishikawa3,
  6. Shoji Kamiura2,
  7. Shin-ichi Nakatsuka1
  1. 1 Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan
  2. 2 Department of Gynecology, Osaka International Cancer Institute, Osaka, Japan
  3. 3 Department of Hematology, Osaka International Cancer Institute, Osaka, Japan
  1. Correspondence to Dr Harumi Nakamura, Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka 541-8567, Japan; nakamura-ha{at}

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Clinical question

A 50-year-old woman presented with a very hard goose-egg size bulky mass of the uterine cervix, involving the uterine corpus and vaginal wall. Histology specimens were obtained via needle biopsies of the cervix. Review the high-quality, interactive digital Aperio slides at and and consider your diagnosis.

What is your diagnosis?

  1. Chronic cervicitis

  2. Soft tissue sarcoma

  3. Spindle cell carcinoma

  4. A spindle cell variant of diffuse large B-cell lymphoma (DLBCL)

  5. Spindle cell melanoma

The correct answer is after the discussion.


The adnexa was the most common site (56%) of primary genital tract lymphoma, followed by the corpus (15%) then the cervix (11%).1 DLBCL evidently …

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  • Handling editor Iskander Chaudhry.

  • Contributors HN wrote the manuscript with support from HM, MK and SK. JI, SK and S-iN helped supervise the project.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.