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Virtual case of the month
Rare and unusual spindle cell tumour
  1. Harumi Nakamura1,
  2. Masanori Kitamura1,
  3. Hiroko Murata2,
  4. Shuhei Kida3,
  5. Jun Ishikawa3,
  6. Shoji Kamiura2,
  7. Shin-ichi Nakatsuka1
  1. 1 Department of Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka, Japan
  2. 2 Department of Gynecology, Osaka International Cancer Institute, Osaka, Japan
  3. 3 Department of Hematology, Osaka International Cancer Institute, Osaka, Japan
  1. Correspondence to Dr Harumi Nakamura, Diagnostic Pathology and Cytology, Osaka International Cancer Institute, Osaka 541-8567, Japan; nakamura-ha{at}mc.pref.osaka.jp

https://doi.org/10.1136/jclinpath-2019-206144

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    Clinical question

    A 50-year-old woman presented with a very hard goose-egg size bulky mass of the uterine cervix, involving the uterine corpus and vaginal wall. Histology specimens were obtained via needle biopsies of the cervix. Review the high-quality, interactive digital Aperio slides at http://virtualacp.com/JCPCases/jclinpath-2019-206144_A and http://virtualacp.com/JCPCases/jclinpath-2019-206144_B and consider your diagnosis.

    What is your diagnosis?

    1. Chronic cervicitis

    2. Soft tissue sarcoma

    3. Spindle cell carcinoma

    4. A spindle cell variant of diffuse large B-cell lymphoma (DLBCL)

    5. Spindle cell melanoma

    The correct answer is after the discussion.

    Discussion

    The adnexa was the most common site (56%) of primary genital tract lymphoma, followed by the corpus (15%) then the cervix (11%).1 DLBCL evidently …

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    Footnotes

    • Handling editor Iskander Chaudhry.

    • Contributors HN wrote the manuscript with support from HM, MK and SK. JI, SK and S-iN helped supervise the project.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; internally peer reviewed.