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Phaeochromocytoma and paraganglioma
  1. Julie Ann Tarling1,
  2. Rajeev Kumar2,
  3. Louise J Ward1,
  4. Christopher Boot3,
  5. WS Wassif1
  1. 1 Clinical Biochemistry, Bedfordshire Hospitals NHS Foundation Trust, Bedford, UK
  2. 2 Diabetes and Endocrinology, Bedfordshire Hospitals NHS Foundation Trust, Bedford, UK
  3. 3 Blood Sciences, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK
  1. Correspondence to Dr Julie Ann Tarling, Clinical Biochemistry, Bedfordshire Hospitals NHS Foundation Trust, Bedford, UK; julie.tarling{at}bedfordhospital.nhs.uk

Abstract

Phaeochromocytomas and paragangliomas are rare catecholamine-producing neuroendocrine tumours which can potentially cause catastrophic crises with high morbidity and mortality. This best practice article considers the causes and presentation of such tumours, screening and diagnostic tests, management of these patients and consideration of family members at risk.

  • CATECHOLAMINES
  • Adrenal Glands
  • Endocrine System Diseases
  • Neuroendocrine Tumors

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Footnotes

  • Handling editor Patrick J Twomey.

  • Contributors JAT and WW contributed to the conception and design of the paper and wrote the first draft, which has been edited and approved by all authors for the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed.

  • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.