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Fibrosing organising pneumonia
  1. Brooke Beardsley1,
  2. Doris Rassl2
  1. 1Department of Anatomical Pathology, Canterbury Health Laboratories, Christchurch, New Zealand
  2. 2Department of Histopathology, Papworth Hospital, Cambridge, UK
  1. Correspondence to Dr Doris Rassl, Department of Histopathology, Sims Woodhead Building, Papworth Hospital, Papworth Everard, Cambridge CB23 3RE, UK; doris.rassl{at}papworth.nhs.uk

Abstract

Organising pneumonia (otherwise referred to as bronchiolitis obliterans organising pneumonia) is characterised histologically by plugs of granulation tissue, which are present predominantly within small airways, alveolar ducts and peri-bronchiolar alveoli. This pattern is not specific for any disorder or cause, but is one type of inflammatory response to pulmonary injury, which may be seen in a wide variety of clinical conditions. Typically, organising pneumonia responds very well to corticosteroid treatment; however, a small percentage of patients appear to develop progressive fibrosis.

  • Lung
  • Inflammation
  • fibrosis

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