Article Text

other Versions

Download PDFPDF
Message in a bottle: decoding medication injury patterns in the gastrointestinal tract
  1. Lysandra Voltaggio1,
  2. Dora Lam-Himlin2,
  3. Berkeley N Limketkai3,
  4. Aatur D Singhi4,
  5. Christina A Arnold5
  1. 1Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland, USA
  2. 2Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, Arizona, USA
  3. 3Department of Medicine, Stanford University, Stanford, California, USA
  4. 4Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
  5. 5Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA
  1. Correspondence to Dr Christina A Arnold, Department of Pathology, The Ohio State University Wexner Medical Center, N337-C Doan Hall; 410 W. 10th Avenue, Columbus, OH 43210-1228, USA; carnold77{at}


Medication injury in the gastrointestinal tract (GIT) is a rapidly evolving topic. Increasing endoscopy together with an ageing population, polypharmacy, and a burgeoning drug industry offer heightened opportunities to observe the unintended side effects of therapeutic ingestants. In this review, we emphasise the most commonly encountered medication injuries involving the GIT, as well as emerging agents and mimics. While topics are organised by organ system, the reader should keep in mind that injury patterns are generally not site-specific. As such, awareness of these major morphologic patterns can be translated to multiple tissue sites to more broadly facilitate the diagnostic process.

  • BMT

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.