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  • Decreasing formalin concentration improves quality of DNA extracted from formalin-fixed paraffin-embedded tissue specimens without compromising tissue morphology or immunohistochemical staining

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Decreasing formalin concentration improves quality of DNA extracted from formalin-fixed paraffin-embedded tissue specimens without compromising tissue morphology or immunohistochemical staining

Authors

  • Michele Cummings Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Henry King Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • James Hurst Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Georgette Tanner Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Leah Khazin Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Phillip Thompson Department of Histopathology, St. James's University Hospital, Leeds, UK PubMed articlesGoogle scholar articles
  • Allan Gray Department of Histopathology, St. James's University Hospital, Leeds, UK PubMed articlesGoogle scholar articles
  • Narinder Gahir Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Caroline Cartlidge Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Zara Farooq Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Keyura Raveendran Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  • Katie Allen Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK Department of Histopathology, St. James's University Hospital, Leeds, UK PubMed articlesGoogle scholar articles
  • Olorunda Rotimi Department of Histopathology, St. James's University Hospital, Leeds, UK PubMed articlesGoogle scholar articles
  • Nicolas M Orsi Women's Health Research Group, Pathology & Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Leeds, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Nicolas M Orsi, Pathology and Data Analytics, Leeds Institute of Medical Research at St. James's, University of Leeds, Wellcome Trust Brenner Building, Beckett St., Leeds LS9 7TF, UK; n.m.orsi{at}leeds.ac.uk
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Citation

Cummings M, King H, Hurst J, et al
Decreasing formalin concentration improves quality of DNA extracted from formalin-fixed paraffin-embedded tissue specimens without compromising tissue morphology or immunohistochemical staining
Journal of Clinical Pathology 2020;73:514-518.

Publication history

  • Received December 10, 2019
  • Revised December 16, 2019
  • Accepted December 17, 2019
  • First published January 9, 2020.
Online issue publication 
November 15, 2022

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© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.