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Virtual case of the month
Unusual skin tumour with a large cystic component
  1. Akira Ishikawa1,
  2. Kazuya Kuraoka1,2,
  3. Junichi Zaitsu2,
  4. Akihisa Saito2,
  5. Sari Fujimoto3,
  6. Takahiro Uemura3,
  7. Kiyomi Taniyama4
  1. 1Department of Clinical Laboratory, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Kure, Japan
  2. 2Department of Diagnostic Pathology, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Kure, Japan
  3. 3Department of Plastic Surgery, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Kure, Japan
  4. 4Honorary President, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Kure, Japan
  1. Correspondence to Dr Kazuya Kuraoka, Department of Clinical Laboratory, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, Kure, 737-0023, Japan; kuraoka.kazuya.vk{at}mail.hosp.go.jp

https://doi.org/10.1136/jclinpath-2020-206785

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    Clinical question

    An 80-year-old woman presented to our hospital with a tumour on the left lower leg. The lesion had slowly grown over the last year. She had no personal or family history of skin cancer. The lesion of concern was cystic and consisted of double 10 mm nodules in diameter. The clinical appearance of the lesion raised suspicion of malignancy and surgical resection was performed. The surgically-resected specimen was 22×15×14 mm in size, and the nodule had a yellowish serous fluid.

    Differential diagnoses

    1. Nodular hidradenoma

    2. Atypical hidradenoma

    3. Hidradenocarcinoma

    4. Poroma

    5. Trichilemmoma

    Discussion

    Hidradenocarcinoma is an uncommon malignant tumour in a sweat gland. Generally, sweat gland carcinomas are rare with a reported incidence of approximately 0.05%. Hidradenocarcinomas account …

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    Footnotes

    • Handling editor Iskander Chaudhry.

    • Contributors AI made a substantial contribution towards the concept and design of the case report. JZ, AS, SF, TU and KT were involved in drafting the manuscript and critical revision for intellectual content. KK approved the final version of the manuscript submitted for publication. All authors read and approved the final manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Not required.

    • Provenance and peer review Not commissioned; internally peer reviewed.