Footnotes

• Handling editor Runjan Chetty.

• Contributors HH conceived the idea of the paper and led in the drafting. LB, KO'C and MK were involved in all decisions on content, reviewed all drafts, contributed aspects relevant to their discipline and expertise, and all authors reviewed and agreed the final draft.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests HH has received funding for research from Pfizer and Astellas in recent years and has also received a consulting fee from Pfizer. MK has received conference sponsorship from Takeda, and a speaker’s honoraria from Biogen. LB and KO'C have no conflicts of interest to declare.

• Provenance and peer review Not commissioned; internally peer reviewed.