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Tumour-to-tumour metastasis of breast cancer (donor) and clear cell renal cell carcinoma (recipient): a case report
  1. Justin Hau1,2,
  2. Joana Briosa Neves1,
  3. Mary Varia1
  1. 1Cellular Pathology Department, St Thomas' Hospital, London, UK
  2. 2Cellular Pathology Department, Royal Sussex County Hospital, Brighton, UK
  1. Correspondence to Dr Justin Hau; justin.hau{at}

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A woman in her late 70s was referred to urology clinic to consider intervention for a biopsy-proven 24 mm WHO/International Society of Urological Pathology (ISUP) grade 1 clear cell renal cell carcinoma (CCRCC) that was diagnosed 4 years prior and managed with active surveillance up to that point.

The patient had a history of right invasive breast cancer (ductal carcinoma) first diagnosed more than 20 years ago and treated with wide local excision and adjuvant radiotherapy. She developed breast cancer recurrence in the scalp and chest wall 3 years before and was treated with letrozole, with satisfactory disease control.

Following her urology appointment, the patient opted to undergo a partial nephrectomy. Macroscopic examination of the partial nephrectomy specimen revealed a 33 mm solid yellow tumour containing multiple, discrete tan-brown nodules.

Microscopic analysis revealed the solid yellow …

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  • Handling editor Murali Varma.

  • Contributors All authors were involved in planning, conduct, reporting, conception and design, acquisition of data, analysis, data interpretation, writing and reviewing of the manuscript.

  • Funding None

  • Competing interests None

  • Provenance and peer review Not commissioned; externally peer reviewed.