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Evaluating ChatGPT in pathology: towards multimodal AI in medical imaging
  1. Shunsuke Koga
  1. Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
  1. Correspondence to Dr Shunsuke Koga, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA; shunsuke.koga{at}pennmedicine.upenn.edu

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I read with great interest the manuscript by Laohawetwanit et al, which evaluates the performance of Chat Generative Pre-trained Transformer (ChatGPT) in detecting and classifying colorectal adenomas from histopathological images.1 The study reports that ChatGPT achieved a median sensitivity of 74% and a specificity of 36% for adenoma detection, with an overall median accuracy of 56%. It further demonstrates variable accuracy in polyp classification, with notably low specificity and considerable inconsistency in diagnostic outputs, as indicated by kappa values ranging from 0.06 to 0.11. These findings highlight both the potential and limitations of applying advanced language models to the analysis of histopathological images in colorectal adenoma detection and classification.

The distinction between artificial intelligence (AI) …

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Footnotes

  • Handling editor Runjan Chetty.

  • Twitter @shunsuke_koga

  • Contributors SK developed the original concept and drafted the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.