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BMJ Journals

Online First

December 05, 2022

Original research
GTF2I mutation in micronodular thymoma with lymphoid stroma

Andrea Bille, Katherine Fryer, Andrew Wallace, Daisuke Nonaka

doi: 10.1136/jcp-2022-208655
Original research
Prognostic value and tumour microenvironment characteristics of the Glasgow Microenvironment Score in primary triple-negative breast cancer

Xunxi Lu, Yue Wang, Mengting He, Zongchao Gou

doi: 10.1136/jcp-2022-208601

December 01, 2022

Original research
Clinicopathological and genetic analyses of pulmonary enteric adenocarcinoma

Fumi Okada, Maiko Takeda, Tomomi Fujii, Tomoko Uchiyama, Shoh Sasaki, Minami Matsuoka, Yuji Nitta, Chiyoko Terada, Katsuya Maebo, Kohei Morita, Eiwa Ishida, Noriyoshi Sawabata, Chiho Ohbayashi

doi: 10.1136/jcp-2022-208583

November 21, 2022

Original research
Prognostic value of KRAS mutations, TP53 mutations and PD-L1 expression among lung adenocarcinomas treated with immunotherapy

Ea Maria Tønning Tønnesen, Magnus Stougaard, Peter Meldgaard, Johanne Lade-Keller

doi: 10.1136/jcp-2022-208574

November 14, 2022

Original research
Quality metrics for enhanced performance of an NGS panel using single-vial amplification technology

Subit Barua, Susan Hsiao, Emily Clancy, Christopher Freeman, Mahesh Mansukhani, Helen Fernandes

doi: 10.1136/jcp-2022-208536

November 08, 2022

Original research
Comparative analyses of tumour immune microenvironment between collecting duct carcinoma and fumarate hydratase-deficient renal cell carcinoma

Daisuke Kiyozawa, Kenichi Kohashi, Dai Takamatsu, Shinya Umekita, Masatoshi Eto, Mitsuru Kinjo, Kenichi Nishiyama, Kenichi Taguchi, Yumi Oshiro, Yusuke Kuboyama, Yoshinao Oda

doi: 10.1136/jcp-2022-208589

November 03, 2022

Original research
Use of the ISUP e-learning module improves interrater reliability in prostate cancer grading

Rachel N Flach, Lars Egevad, Martin Eklund, Theodorus H van der Kwast, Brett Delahunt, Hemamali Samaratunga, Britt B M Suelmann, Peter-Paul M Willemse, Richard P Meijer, Paul J van Diest

doi: 10.1136/jcp-2022-208506

November 02, 2022

Original research
KIT genetic alterations in breast cancer

Mahsa Vahdatinia, Fatemeh Derakhshan, Arnaud Da Cruz Paula, Higinio Dopeso, Antonio Marra, Andrea M Gazzo, David Brown, Pier Selenica, Dara S Ross, Pedram Razavi, Hong Zhang, Britta Weigelt, Hannah Y Wen, Edi Brogi, Jorge S Reis-Filho, Fresia Pareja

doi: 10.1136/jcp-2022-208611

November 01, 2022

Original research
Correlation between PD-L1 expression of the tumour cells and lymphocytes infiltration in the invasive front of urothelial carcinoma

Xiaohu Chen, Hanbin Chen, Rixu Lin, Yulian Li, Ying Guo, Qi Chen, Yanyan Zhang, Guoping Cai, Mengjun Hu, Guorong Chen

doi: 10.1136/jcp-2021-207795
Original research
Preferential MGMT hypermethylation in SDH-deficient wild-type GIST

Olivier T Giger, Rogier ten Hoopen, David Shorthouse, Shukri Abdullahi, Venkata Ramesh Bulusu, Saili Jadhav, Eamonn R Maher, Ruth T Casey

doi: 10.1136/jcp-2022-208462

October 26, 2022

Original research
Multivariate evaluation of prognostic markers in synovial sarcoma

Ana-Belen Larque, Santiago Lozano-Calderon, Gregory M Cote, Yen-Lin Chen, Yin P Hung, Vikram Deshpande, G Petur Nielsen, Ivan Chebib

doi: 10.1136/jcp-2022-208518

September 23, 2022

Original research
Barrett’s oesophagus with indefinite for dysplasia shows high rates of prevalent and incident neoplasia in a UK multicentre cohort

Maja Kopczynska, Elizabeth Ratcliffe, Harika Yalamanchili, Anna Thompson, Adib Nimri, James Britton, Yeng Ang

doi: 10.1136/jcp-2022-208524

September 19, 2022

Original research
Molecular characterisation of Hb Akron [β52 (D3) Asp→Val] combined with thalassaemia in a Chinese family

Sheng He, Bolian Wang, Shang Yi, Zhenyan Huang, Lifang Liang, Zhenren Peng, Pengshu Song, Biyan Chen, Faqin Chen, Hongwei Wei

doi: 10.1136/jcp-2021-208133

September 16, 2022

Original research
IGH cytogenetic abnormalities can be detected in multiple myeloma by imaging flow cytometry

Henry Hui, Kathy A Fuller, Luna Eresta Jaya, Yusuke Konishi, Teng Fong Ng, Richard Frodsham, Graham Speight, Kazuhiro Yamada, Sarah E Clarke, Wendy N Erber

doi: 10.1136/jcp-2022-208230

September 13, 2022

Original research
Thrombin generation assay and lupus anticoagulant synergically distinguish populations of patients with antiphospholipid antibodies

Massimo Radin, Alice Barinotti, Irene Cecchi, Silvia Grazietta Foddai, Elena Rubini, Dario Roccatello, Elisa Menegatti, Savino Sciascia

doi: 10.1136/jcp-2022-208199

September 08, 2022

Original research
Polymorphisms of ACE and thrombophilic genes: risk for recurrent pregnancy loss

Olivera Miljanović, Vesna Ilić, Slađana Teofilov, Bojana Cikota-Aleksić, Zvonko Magić

doi: 10.1136/jcp-2021-208057

September 06, 2022

Original research
Independent reporting in oral and maxillofacial pathology

Riddhi Gorania, Keith Hunter, Gillian Hall, Daniel J Brierley

doi: 10.1136/jcp-2022-208495

September 05, 2022

Original research
Comparison of two pathological processing methods for large endoscopic submucosal dissection (ESD) specimens

Zixiang Yu, Dongxian Jiang, Wen Huang, Rongkui Luo, Haixing Wang, Jieakesu Su, Jia Liu, Chen Xu, Yingyong Hou

doi: 10.1136/jcp-2022-208491

September 01, 2022

Original research
Proposal to distinguish HER2-low from HER2-normal breast cancer by in situ hybridisation

Yen-Ying Chen, Ching-Fen Yang, Chih-Yi Hsu

doi: 10.1136/jcp-2022-208444

August 30, 2022

Original research
Increasing test specificity without impairing sensitivity: lessons learned from SARS-CoV-2 serology
Free

Thomas Perkmann, Thomas Koller, Nicole Perkmann-Nagele, Maria Ozsvar-Kozma, David Eyre, Philippa Matthews, Abbie Bown, Nicole Stoesser, Marie-Kathrin Breyer, Robab Breyer-Kohansal, Otto C Burghuber, Slyvia Hartl, Daniel Aletaha, Daniela Sieghart, Peter Quehenberger, Rodrig Marculescu, Patrick Mucher, Astrid Radakovics, Miriam Klausberger, Mark Duerkop, Barba Holzer, Boris Hartmann, Robert Strassl, Gerda Leitner, Florian Grebien, Wilhelm Gerner, Reingard Grabherr, Oswald F Wagner, Christoph J Binder, Helmuth Haslacher

doi: 10.1136/jcp-2022-208171

August 25, 2022

Original research
Quantification of human embryonic ζ-globin chains in Southeast Asian deletion (--^SEA) carriers

Yuhua Ye, Guoying Sun, Zhe Ren, Yidan Liang, Hualei Luo, Peng Lin, Xingmin Wang, Zejun Dong, Li Huang, Lang Qin, Wenfang Yu, Ge Wang, Yuqiu Zhou, Jia Tang, Jiwu Lou, Yanhui Liu, Xianqi Zeng, Yajun Chen, Yihong Li, Qianqian Zhang, Jin Huang, Ping Zhu, Liang Lin, Xinhua Zhang, Xiangmin Xu

doi: 10.1136/jcp-2022-208159

August 23, 2022

Original research
Establishment and validation of prognostic nomograms integrating histopathological features in patients with endocervical adenocarcinoma

Rong-Zhen Luo, Xia Yang, Shi-Wen Zhang, Li-Li Liu

doi: 10.1136/jcp-2021-208064
Original research
Performance evaluation and clinical impact of the Oncomine Myeloid Research Assay for gene expression analysis in myeloid haematologic malignancies

Min Ji Jeon, Eun Sang Yu, Dae Sik Kim, Chul Won Choi, Ha Nui Kim, Jeong Ah Kwon, Soo-Young Yoon, Jung Yoon

doi: 10.1136/jcp-2022-208425

July 29, 2022

Original research
Impact of the transition to digital pathology in a clinical setting on histopathologists in training: experiences and perceived challenges within a UK training region

Lisa Browning, Lucinda Winter, Rosalin A Cooper, Abhisek Ghosh, Thomas Dytor, Richard Colling, Eve Fryer, Jens Rittscher, Clare Verrill

doi: 10.1136/jcp-2022-208416

July 21, 2022

Original research
Automatic CD30 scoring method for whole slide images of primary cutaneous CD30⁺ lymphoproliferative diseases

Tingting Zheng, Song Zheng, Ke Wang, Hao Quan, Qun Bai, Shuqin Li, Ruiqun Qi, Yue Zhao, Xiaoyu Cui, Xinghua Gao

doi: 10.1136/jcp-2022-208344

July 12, 2022

Original research
Idylla EGFR assay on extracted DNA: advantages, limits and place in molecular screening according to the latest guidelines for non-small-cell lung cancer (NSCLC) patients

Emmanuel Khalifa, Caroline Chapusot, Benjamin Tournier, Julie Sentis, Estelle Marion, Alicia Remond, Manon Aubry, Célia Pioche, Anthony Bergeron, Charlotte Primois, Larry Blanchard, Alice Millière, Marlène Boucheix, Yannick Léger, Marine Bairrao, Véronique Brouste, Laurent Martin, Isabelle Soubeyran

doi: 10.1136/jcp-2022-208325
Original research
Verification and validation of the anti-PD-L1 antibody, Clone 22C₃ on a laboratory-developed test

Shane Brennan, Julie O'Neill, Susan Kennedy

doi: 10.1136/jclinpath-2022-208353

June 23, 2022

Original research
Predicting the likelihood of a BRCA1/2 pathogenic variant being somatic by testing only tumour DNA in non-mucinous high-grade epithelial ovarian cancer

Robert D Morgan, George J Burghel, Nicola Flaum, Michael Bulman, Philip Smith, Andrew R Clamp, Jurjees Hasan, Claire Mitchell, Zena Salih, Emma R Woodward, Fiona Lalloo, Joseph Shaw, Sudha Desai, Emma J Crosbie, Richard J Edmondson, Helene Schlecht, Andrew J Wallace, Gordon C Jayson, D Gareth R Evans

doi: 10.1136/jcp-2022-208369

June 14, 2022

Original research
New autopsy technique in COVID-19 positive dead bodies: opening the thoracic cavity with an outlook to reduce aerosol spread
Free

Somnath Das, Anshuman Roy, Rina Das

doi: 10.1136/jclinpath-2022-208173
Original research
Update regarding the role of PD-L1 in oncocytic thyroid lesions on cytological samples

Marco Dell'Aquila, Pietro Tralongo, Alessia Granitto, Maurizio Martini, Sara Capodimonti, Mariangela Curatolo, Vincenzo Fiorentino, Alfredo Pontecorvi, Guido Fadda, Celestino Pio Lombardi, Maco Raffaelli, Liron Pantanowitz, Luigi Maria Larocca, Esther Diana Rossi

doi: 10.1136/jclinpath-2022-208215
Original research
One-step genotyping of α-thalassaemia by multiplex symmetric PCR melting curve

Jiachun Qin, Jun He, Yang Li, Nansong Liu, Fangchao Tao, Pengyi Zhang, Weilin Guo, Qiongzhen Qin, Wanjun Zhou

doi: 10.1136/jclinpath-2022-208363

May 16, 2022

Original research
Beyond the routine CBC: machine learning and statistical analyses identify research CBC parameter associations with myelodysplastic syndromes and specific underlying pathogenic variants

Olga Pozdnyakova, Radu Stefan Niculescu, Tracey Kroll, Lisa Golemme, Nolan Raymond, Debra Briggs, Annette Kim

doi: 10.1136/jclinpath-2021-207860

May 09, 2022

Original research
Development of a LAG-3 immunohistochemistry assay for melanoma

Lori Johnson, Bryan McCune, Darren Locke, Cyrus Hedvat, John B Wojcik, Caitlin Schroyer, Jim Yan, Krystal Johnson, Angela Sanders-Cliette, Sujana Samala, Lloye M Dillon, Steven Anderson, Jeffrey Shuster

doi: 10.1136/jclinpath-2022-208254
Original research
Postmortem survey of haemoglobin A1c, non-alcoholic steatohepatitis and liver fibrosis within a general population

Kristina-Ana Klaric, Jacqueline Louise Parai, Charis Anthea Kepron, Alfredo Eugene Walker, Christopher Mark Milroy

doi: 10.1136/jclinpath-2021-207998

April 08, 2022

Original research
Overexpression of integrin alpha 2 (ITGA2) correlates with poor survival in patients with pancreatic ductal adenocarcinoma

Steffen Deichmann, Leif Schindel, Rüdiger Braun, Louisa Bolm, Martin Taylor, Vikram Deshpande, Oliver Schilling, Peter Bronsert, Tobias Keck, Cristina Ferrone, Ulrich Wellner, Kim Honselmann

doi: 10.1136/jclinpath-2022-208176

March 22, 2022

Original research
Diagnostic utility of ERG immunostaining in dermatofibroma

Yuichi Yamada, Toshio Ichiki, Yosuke Susuki, Yui Yamada-Nozaki, Yuki Tateishi, Masutaka Furue, Yoshinao Oda

doi: 10.1136/jclinpath-2022-208158

March 10, 2022

Original research
Dual resolution deep learning network with self-attention mechanism for classification and localisation of colorectal cancer in histopathological images

Yan Xu, Liwen Jiang, Shuting Huang, Zhenyu Liu, Jiangyu Zhang

doi: 10.1136/jclinpath-2021-208042

March 07, 2022

Original research
FOCUS4 biomarker laboratories: from the benefits to the practical and logistical issues faced during 6 years of centralised testing

Susan D Richman, Gemma Hemmings, Helen Roberts, Niall Gallop, Rachel Dodds, Lyndsay Wilkinson, Jonathan Davis, Rhian White, Emma Yates, Bharat Jasani, Louise Brown, Tim S Maughan, Rachel Butler, Philip Quirke, Richard Adams

doi: 10.1136/jclinpath-2022-208233

February 15, 2022

Original research
Compound computer vision workflow for efficient and automated immunohistochemical analysis of whole slide images

Michael Kyung Ik Lee, Madhumitha Rabindranath, Kevin Faust, Jennie Yao, Ariel Gershon, Noor Alsafwani, Phedias Diamandis

doi: 10.1136/jclinpath-2021-208020

February 10, 2022

Original research
MMR profile and microsatellite instability status in colorectal mucinous adenocarcinoma with synchronous metastasis: a new clue for the clinical practice

Paola Parente, Umberto Malapelle, Valentina Angerilli, Mariangela Balistreri, Sara Lonardi, Salvatore Pucciarelli, Caterina De Luca, Francesco Pepe, Gianluca Russo, Elena Vigliar, Angela Danza, Fabio Scaramuzzi, Giancarlo Troncone, Paolo Graziano, Matteo Fassan

doi: 10.1136/jclinpath-2022-208143

February 08, 2022

Original research
Agreement between L1 and E6/E7-based assays for detection of high-risk HPV in cervical, oropharyngeal and penile cancers

Elia Alcaniz Boada, Kate Cuschieri, Catriona Graham, Sharon Moncur, Ramya Bhatia

doi: 10.1136/jclinpath-2021-208054

January 31, 2022

Original research
Preference of grade and lymphovascular invasion over invasive size measurement in stage I lung adenocarcinoma

Hiroe Itami, Takeshi Kawaguchi, Daiki Yoshikawa, Takashi Watanabe, Chiyoko Terada, Fumi Okada, Tomoko Uchiyama, Maiko Takeda, Eiwa Ishida, Yuko Nishimoto, Hiroshi Okada, Keiji Kushibe, Noriyoshi Sawabata, Chiho Ohbayashi

doi: 10.1136/jclinpath-2021-208053

January 17, 2022

Original research
Coronial postmortem reports and indirect COVID-19 pandemic-related mortality

Robert Pell, S Kim Suvarna, Nigel Cooper, Guy Rutty, Anna Green, Michael Osborn, Peter Johnson, Alison Hayward, Justine Durno, Theodore Estrin-Serlui, Marion Mafham, Ian S D Roberts

doi: 10.1136/jclinpath-2021-208003
Original research
GATA3 positivity is associated with poor prognosis in patients with oesophageal squamous cell carcinoma

Zhikai Chi, Jyoti Balani, Purva Gopal, Suntrea Hammer, Jing Xu, Lan Peng

doi: 10.1136/jclinpath-2021-208035
Original research
Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas)

Kirsty Wells, Angela Lamrca, George Papaxoinis, Andrew Wallace, Anne Marie Quinn, Yvonne Summers, Daisuke Nonaka

doi: 10.1136/jclinpath-2021-207837

December 10, 2021

Grand rounds commentary
Through the looking crystal: clarifying the pathogenesis and laboratory work-up of cryocrystalglobulinaemia

Rivak Punchoo

doi: 10.1136/jclinpath-2021-207585
Grand rounds
57-year-old woman with purpura fulminans and acute kidney injury

Tao Su, Qizhuang Jin, Tao Zhao, Suxia Wang

doi: 10.1136/jclinpath-2020-207020

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