You are here

Article Text

Article menu
Download PDFPDF
Research Article
Chlamydia trachomatis detected in human placenta.
  1. M Gencay,
  2. M Puolakkainen,
  3. T Wahlström,
  4. P Ammälä,
  5. L Mannonen,
  6. A Vaheri,
  7. M L Koskiniemi
  1. Department of Virology, Haartman Institute, University of Helsinki, Finland.

    Abstract

    AIMS: To evaluate the relation between Chlamydia trachomatis infection and stillbirth, placental tissue was studied for the presence of C trachomatis. METHODS: Paraffin wax embedded placental tissue of a stillbirth fetus, born at the 36th week of gestation to a 21 year old mother with high serum antibody titres to C trachomatis immunotypes during pregnancy and who was culture positive to C trachomatis three years previously, was studied by in situ hybridisation, polymerase chain reaction, and immunohistochemistry for the presence of C trachomatis. RESULTS: C trachomatis was detected in placental specimens by in situ hybridisation and alkaline phosphatase antialkaline phosphatase staining in several sections, whereas control tissues were uniformly negative, indicating the presence of C trachomatis nucleic acid and antigen in the placenta. CONCLUSION: This is the first reported case in which C trachomatis has been demonstrated in the human placenta.

    https://doi.org/10.1136/jcp.50.10.852

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.