TY - JOUR T1 - Studies on the blood lipids and lipoproteins in thalassaemia and sickle cell anaemia JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 361 LP - 364 DO - 10.1136/jcp.14.4.361 VL - 14 IS - 4 AU - C. Choremis AU - V. Kyriakidès AU - E. Papadakis Y1 - 1961/07/01 UR - http://jcp.bmj.com/content/14/4/361.abstract N2 - In Cooley's anaemia the serum lipid fraction, determined by chemical analysis, was found to be decreased. The lipoprotein distribution by paper electrophoresis showed a characteristic pattern with abnormally low α1 fraction and high concentrations of the β fractions. There is no relationship between age and serum lipoprotein distribution. A correlation was found between the electrophoretic pattern, liver function tests, and the E/C index. Similar changes but of lesser degree were found in sickle cell anaemia. Liver damage is thought to be the probable cause of the reduced α1 fraction. ER -