RT Journal Article
SR Electronic
T1 Considerations for uniform and accurate biospecimen labelling in a biorepository and research environment
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 634
OP 636
DO 10.1136/jcp.2010.080655
VO 64
IS 7
A1 Kay, Andrew B
A1 Estrada, Daniel K
A1 Mareninov, Sergey
A1 Silver, Steven S
A1 Magyar, Clara E
A1 Dry, Sarah M
A1 Cloughesy, Timothy F
A1 Yong, William H
YR 2011
UL http://jcp.bmj.com/content/64/7/634.abstract
AB Correct labelling of specimens in a biorepository or research laboratory is vital, especially for translational or clinical studies linking clinical data with biospecimens. While patient privacy must be carefully protected, confusing or inadequate labelling can potentially result in the study of the wrong biospecimens with detrimental effects to the accuracy of published findings or a requirement for invaluable biospecimens to be discarded. Labelling guidelines are described in the biorepository of the University of California–Los Angeles Brain Tumour Translational Resource, and in recipient neuro-oncology laboratories to which biospecimens and derivatives are provided. This approach includes specifying identifier types, types of dates and institutions on the biospecimen labels; using multiple identifiers on each specimen when feasible; and developing a three to four-letter alphanumeric code to aid in label recognition. In addition, steps are being taken to educate recipient laboratories on best practices in labelling.