RT Journal Article SR Electronic T1 Extensive intracranial lesions in a case of orbital non-specific granuloma combined with polyarteritis nodosa JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 137 OP 143 DO 10.1136/jcp.16.2.137 VO 16 IS 2 A1 K. E. Åström A1 S. O. Lidholm YR 1963 UL http://jcp.bmj.com/content/16/2/137.abstract AB A unique case of a non-specific orbital granuloma in a 65-year-old woman is described. Necropsy disclosed extensive spread of the granuloma to the pachy- and leptomeninges as well as elsewhere. There were also signs of generalized polyarteritis nodosa. For five years the patient had severe facial pain and for four years signs of impaired renal function. A psychosis developed two months before her death. Previously she had had infections in the upper respiratory pathways and bilateral episcleritis. The nosology, aetiology, and pathogenesis of the condition are discussed.