PT - JOURNAL ARTICLE AU - Waldron, H. A. TI - Urinary amino-acetone excretion in lead workers AID - 10.1136/jcp.18.2.230 DP - 1965 Mar 01 TA - Journal of Clinical Pathology PG - 230--234 VI - 18 IP - 2 4099 - http://jcp.bmj.com/content/18/2/230.short 4100 - http://jcp.bmj.com/content/18/2/230.full SO - J Clin Pathol1965 Mar 01; 18 AB - Urinary amino-acetone concentrations were determined in a group of 51 persons with industrial exposure to lead and the findings compared with those obtained from a control group of 27 persons having no exposure to lead. A good correlation was found between delta-aminolaevulinic acid and amino-acetone excretion in the control group but this correlation was not so well defined in the lead-exposed group. In this group excretion of amino-acetone seemed to be better correlated with excretion of delta-aminolaevulinic acid for values less than 0·6 mg.% than with values greater than 0·6 mg.%. All the men concerned in the investigation were employed in dusty occupations. Hypotheses are put forward to attempt to explain the differences in excretion of amino-acetone noted amongst lead workers with high excretion of delta aminolaevulinic acid. Little correlation was found between amino-acetone excretion and that of either porphobilinogen or coproporphyrin.