RT Journal Article
SR Electronic
T1 Urinary amino-acetone excretion in lead workers
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 230
OP 234
DO 10.1136/jcp.18.2.230
VO 18
IS 2
A1 Waldron, H. A.
YR 1965
UL http://jcp.bmj.com/content/18/2/230.abstract
AB Urinary amino-acetone concentrations were determined in a group of 51 persons with industrial exposure to lead and the findings compared with those obtained from a control group of 27 persons having no exposure to lead. A good correlation was found between delta-aminolaevulinic acid and amino-acetone excretion in the control group but this correlation was not so well defined in the lead-exposed group. In this group excretion of amino-acetone seemed to be better correlated with excretion of delta-aminolaevulinic acid for values less than 0·6 mg.% than with values greater than 0·6 mg.%. All the men concerned in the investigation were employed in dusty occupations. Hypotheses are put forward to attempt to explain the differences in excretion of amino-acetone noted amongst lead workers with high excretion of delta aminolaevulinic acid. Little correlation was found between amino-acetone excretion and that of either porphobilinogen or coproporphyrin.