PT - JOURNAL ARTICLE AU - B. A. Saggers AU - David Lawson TI - Some observations on the penetration of antibiotics through mucus <em>in vitro</em> AID - 10.1136/jcp.19.4.313 DP - 1966 Jul 01 TA - Journal of Clinical Pathology PG - 313--317 VI - 19 IP - 4 4099 - http://jcp.bmj.com/content/19/4/313.short 4100 - http://jcp.bmj.com/content/19/4/313.full SO - J Clin Pathol1966 Jul 01; 19 AB - A study has been made on the penetration values in vitro of antibiotics through hog gastric mucin at pH 7ยท4. Determinations have also been done on the binding of antibiotics to mucus and human plasma. The mucolytic agent N-acetyl cysteine has been studied in regard to its effect on antibiotics penetrating mucus and for any possible inactivation of antibiotics.