PT - JOURNAL ARTICLE AU - R. Rowland AU - C. G. H. Newman TI - Pulmonary complications of oxygen therapy AID - 10.1136/jcp.22.2.192 DP - 1969 Mar 01 TA - Journal of Clinical Pathology PG - 192--198 VI - 22 IP - 2 4099 - http://jcp.bmj.com/content/22/2/192.short 4100 - http://jcp.bmj.com/content/22/2/192.full SO - J Clin Pathol1969 Mar 01; 22 AB - Three cases of the neonatal respiratory distress syndrome are described. The babies were treated by prolonged oxygen given by intermittent positive pressure respiration after endotracheal intubation. Two of the infants died and at necropsy the lungs in both cases were consolidated. Both showed widespread haemorrhagic exudate and interstitial oedema. Early organization of the exudate was apparent in one case. The third infant survived but developed a similar exudative condition and a `honeycomb' lung. It is suggested that many of the changes found in the lungs of these cases could be attributed to the toxicity of oxygen.