PT - JOURNAL ARTICLE AU - Sheth, N. K. AU - Prankerd, T. A. J. TI - Inherited thrombocytopenia with thrombasthenia AID - 10.1136/jcp.21.2.154 DP - 1968 Mar 01 TA - Journal of Clinical Pathology PG - 154--156 VI - 21 IP - 2 4099 - http://jcp.bmj.com/content/21/2/154.short 4100 - http://jcp.bmj.com/content/21/2/154.full SO - J Clin Pathol1968 Mar 01; 21 AB - A family with congenital thrombocytopenia is described through four generations where the mode of inheritance appears to be an autosomal dominant. Spontaneous bruising of varying severity, menorrhagia, and profuse bleeding at operation necessitating transfusion were predominant in the history. Platelet function tests were performed on the various patients. Platelet aggregation by adenosine diphosphate (ADP) was found to be defective, though liberation of platelet factor III and platelet thromboplastic function were found to be normal when corrected for deficient numbers.