TY - JOUR T1 - Naturally-occurring fusidic acid resistance in staphylococci and its linkage to other resistances JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 555 LP - 560 DO - 10.1136/jcp.19.6.555 VL - 19 IS - 6 AU - R. J. Evans AU - Pamela M. Waterworth Y1 - 1966/11/01 UR - http://jcp.bmj.com/content/19/6/555.abstract N2 - Although Staph. aureus resistant to fusidic acid can be selected in vitro and has been found in vivo following treatment, naturally occurring strains without previous exposure to the drug have not, so far, been reported. Four such strains were isolated in the area of the North West Surrey Group Laboratory between August and September 1965, and six at Hammersmith Hospital during the first four months of 1966. In two of these resistance to fusidic acid was very unstable and its loss was accompanied by loss of resistance to penicillin in the first and to tetracycline and kanamycin in the second, although this strain remained resistant to penicillin. ER -