PT - JOURNAL ARTICLE AU - Pollock, Andrew TI - Factor VIII and antibody levels in plasma fractions prepared by cryoprecipitation AID - 10.1136/jcp.21.5.635 DP - 1968 Sep 01 TA - Journal of Clinical Pathology PG - 635--637 VI - 21 IP - 5 4099 - http://jcp.bmj.com/content/21/5/635.short 4100 - http://jcp.bmj.com/content/21/5/635.full SO - J Clin Pathol1968 Sep 01; 21 AB - Most of the antibody activity of plasma was found to remain in the supernatant fraction following the preparation of factor-VIII-rich cryoprecipitates. The low level of antibody remaining in these cryoprecipitates indicated that they could safely be used as a source of factor VIII for replacement therapy. Washing the cryoprecipitates farther reduced their antibody titres without materially affecting their factor VIII content.