RT Journal Article
SR Electronic
T1 Factor VIII and antibody levels in plasma fractions prepared by cryoprecipitation
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 635
OP 637
DO 10.1136/jcp.21.5.635
VO 21
IS 5
A1 Pollock, Andrew
YR 1968
UL http://jcp.bmj.com/content/21/5/635.abstract
AB Most of the antibody activity of plasma was found to remain in the supernatant fraction following the preparation of factor-VIII-rich cryoprecipitates. The low level of antibody remaining in these cryoprecipitates indicated that they could safely be used as a source of factor VIII for replacement therapy. Washing the cryoprecipitates farther reduced their antibody titres without materially affecting their factor VIII content.