RT Journal Article
SR Electronic
T1 Studies on the <sup>57</sup>Co vitamin B<sub>12</sub> plasma level absorption test
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 569
OP 571
DO 10.1136/jcp.23.7.569
VO 23
IS 7
A1 B. K. Armstrong
A1 H. J. Woodliff
YR 1970
UL http://jcp.bmj.com/content/23/7/569.abstract
AB Results of the 57Co vitamin B12 plasma level absorption test are described in 163 patients. The use of intramuscular carbachol with the test and the presence or absence of current vitamin B12 therapy did not affect the test results. Injection of 1,000 μg of unlabelled vitamin B12 during the test augmented plasma levels in patients with normal absorption but tests without this injection gave satisfactory differentiation between the normal and malabsorption ranges. Results from patients having had a gastrectomy, ileal resection, or a past history of adult coeliac disease are also described. Amongst patients with presumed Addisonian pernicious anaemia, two with unresolved equivocal results and three with falsely normal results were found. The significance of these is discussed.