RT Journal Article SR Electronic T1 A laboratory study of spontaneous platelet aggregation JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 323 OP 327 DO 10.1136/jcp.24.4.323 VO 24 IS 4 A1 Friedlander, I. A1 Cook, I. J. Y. A1 Hawkey, C. A1 Symons, C. YR 1971 UL http://jcp.bmj.com/content/24/4/323.abstract AB During studies on platelet aggregation using the EEL platelet aggregation meter, 8% of the individuals tested were found to have platelets which aggregated spontaneously when citrated, platelet-rich plasma was stirred at 37°C. The EEL aggregation meter differs from other machines in that it incorporates a vertical stirrer which subjects platelets to greater mechanical force. When using this machine it is suggested that spontaneous platelet aggregation is related to increased mechanical fragility of the platelets and low levels of plasma ADP-inhibitor.