RT Journal Article
SR Electronic
T1 Studies of contact activation of blood in haemodialysis
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 1045
OP 1049
DO 10.1136/jcp.25.12.1045
VO 25
IS 12
A1 E. N. Wardle
A1 D. A. Piercy
YR 1972
UL http://jcp.bmj.com/content/25/12/1045.abstract
AB A study of patients on Kiil and Travenol coil dialysis has shown that kallikrein esterase, the kinin precursor, is increased in the venous blood during dialysis and that this is accompanied by an increase in the venous effluent of the dialysers. In addition Hageman factor depletion and an increase of platelet factor 4 has been found in the venous effluent. Such studies indicate surface activation of coagulation in the dialysers and will be of use in future studies of the suitability of different dialysers.