RT Journal Article
SR Electronic
T1 Plasminogen assay by a haemagglutination inhibition technique
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 136
OP 142
DO 10.1136/jcp.24.2.136
VO 24
IS 2
A1 Ludlam, C. A.
A1 Das, P. C.
YR 1971
UL http://jcp.bmj.com/content/24/2/136.abstract
AB Formaldehyde or gluteraldehyde cells treated with tannic acid were coated with plasminogen. These cells are agglutinated by plasminogen antiserum and this reaction can be quantitatively inhibited by purified plasminogen, plasma, and euglobulin. Correlation between this haemagglutination assay and a caseinolytic method is good. The sensitivity of the technique is high and compares favourably with other immunological methods and is approximately 10 times more sensitive than caseinolytic assays. The merits of this type of assay are discussed.