RT Journal Article
SR Electronic
T1 Serum protein levels in primary biliary cirrhosis
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 789
OP 792
DO 10.1136/jcp.25.9.789
VO 25
IS 9
A1 R. N. M. MacSween
A1 C. H. W. Horne
A1 Anne J. Moffat
A1 Hazel M. Hughes
YR 1972
UL http://jcp.bmj.com/content/25/9/789.abstract
AB Serum levels of albumin, transferrin, α2-macroglobulin, β1C/β1A, IgA, IgG, and IgM have been determined in 73 patients with primary biliary cirrhosis and in age- and sex-matched controls. A highly significant fall in albumin was demonstrated, and there were highly significant increases in α2-macroglobulin and all three immunoglobulin levels. Transferrin and β1/Cβ1A levels were unchanged. No significant correlations were found between the titre of antimitochondrial antibody, the duration of symptoms, and any of the serum proteins estimated. A highly significant positive correlation was present between serum albumin and transferrin levels in both patient and control groups.