RT Journal Article
SR Electronic
T1 The effect of serum protein concentrations on the specificity of the radioimmunoassay of carcinoembryonic antigen in malignant neoplasia and non-neoplastic disease
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 130
OP 134
DO 10.1136/jcp.27.2.130
VO 27
IS 2
A1 J. M. Crawley
A1 B. E. Northam
A1 J. P. G. King
A1 J. C. Leonard
A1 S. N. Booth
A1 P. W. Dykes
YR 1974
UL http://jcp.bmj.com/content/27/2/130.abstract
AB Carcinoembryonic antigen (CEA) has been measured in parallel with seven serum proteins and seromucoids in the sera of patients with malignant neoplasia and non-neoplastic disease. In the total group significant correlations were found between CEA and seromucoids and between CEA and several serum proteins. However, with two exceptions, when the individual disease groups were examined no correlation was seen. It is concluded that abnormal concentrations of the specific proteins measured do not consistently interfere in the CEA radioimmunoassay and do not explain the high CEA levels in patients with non-neoplastic diseases.