RT Journal Article
SR Electronic
T1 Immunofluorescence in duodenal mucosa of children with acute enteritis due to a new virus.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 263
OP 266
DO 10.1136/jcp.28.4.263
VO 28
IS 4
A1 Davidson, G P
A1 Goller, I
A1 Bishop, R F
A1 Townley, R R
A1 Holmes, I H
A1 Ruck, B J
YR 1975
UL http://jcp.bmj.com/content/28/4/263.abstract
AB Electron microscopy od duodenal mucosa from children with acute non-bacterial enteritis has shown virus particles in epithelial cells. Indirect immunofluorescent techniques applied to the same tissue showed virus antigen localized in the cytoplasm of epithelial cells of the villi. Specific IgM antibody was present in sera from infected patients as early as two days after the onset of symptoms. Virus particles from different patients appeared to share a common antigen. The evidence presented supports our belief that this new virus was the cause of acute enteritis in the children studied.