RT Journal Article
SR Electronic
T1 Iodine contamination of the serum protein-bound iodine: Incidence and clinical significance
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 319
OP 322
DO 10.1136/jcp.27.4.319
VO 27
IS 4
A1 P. R. Pannall
A1 P. C. Minnaar
A1 A. T. Neser
YR 1974
UL http://jcp.bmj.com/content/27/4/319.abstract
AB Iodine contamination as defined by the combination of a raised (PBI-T4I) difference and low 131I neck uptake was found in 38 (17·5%) of 217 euthyroid patients. Of these, 17 had PBI levels of greater than 20 μg/dl but in the remainder levels were clinically feasible. In only 21 was there a history of exposure to iodine. Two of 12 hypothyroid patients had PBI levels well within normal limits. False elevation of the PBI is thus shown to be common. It is neither always obvious nor can it be easily avoided. The PBI is not an acceptable alternative to T4 estimation by other methods.