RT Journal Article
SR Electronic
T1 The detection of specific IgM antibodies following infection with rubella virus.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 377
OP 382
DO 10.1136/jcp.28.5.377
VO 28
IS 5
A1 J R Pattison
A1 J E Mace
YR 1975
UL http://jcp.bmj.com/content/28/5/377.abstract
AB A gel filtration technique using Sephadex G-200 has been used for the detection of specific IgM in sera from (a) 45 cases of clinical rubella in which diagnostic rises of rubella haemagglutination-inhibiting (HAI) antibody could be demonstrated; (b) 70 cases with clinical evidence of rubella in which a rising titre could not be demonstrated because the first serum sample already had high titre HAI antibodies; and (c) 100 patients in whom rubella was not suspected. The results indicate that the high specificity and sensitivity of the method described make it an appropriate technique for use in the routine diagnosis of acquired rubella.