RT Journal Article
SR Electronic
T1 Effects of minocycline and tetracycline on the vaginal yeast flora.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 403
OP 406
DO 10.1136/jcp.28.5.403
VO 28
IS 5
A1 J D Oriel
A1 P M Waterworth
YR 1975
UL http://jcp.bmj.com/content/28/5/403.abstract
AB Two groups of women with non-specific genital infection were treated for two weeks with tetracycline 250 mg six-hourly and minocycline 100 mg twice daily respectively. Cultures for yeasts were performed before treatment and at the end of the first and second weeks. Before treatment yeasts, mostly Candida albicans, were recovered from 13% of the women. After one and two weeks' treatment yeasts were isolated from 22 and 29% of women treated with tetracycline, and from 19 and 29% of women treated with minocycline. It is concluded that despite inhibition of the growth of yeasts shown by minocycline in vitro, there is no evidence of any significant difference between the actions of tetracycline and minocycline on the vaginal yeast flora.