PT  - JOURNAL ARTICLE
AU  - R A Burnett
TI  - Cor pulmonale due to tumour embolism derived from intrasinusoidal metastatic liver carcinoma.
AID  - 10.1136/jcp.28.6.457
DP  - 1975 Jun 01
TA  - Journal of Clinical Pathology
PG  - 457--464
VI  - 28
IP  - 6
4099  - http://jcp.bmj.com/content/28/6/457.short
4100  - http://jcp.bmj.com/content/28/6/457.full
SO  - J Clin Pathol1975 Jun 01; 28
AB  - Two cases of primary breast carcinoma are described, both terminating in acute cardiorespiratory failure due to multiple tumour micro-embolism. In both cases the source of the emboli was extensive metastatic intrasinusoidal carcinomatous infliltration of the liver. The association of these two uncommon conditions has not previously been reported. A brief review of the literature pertaining to diffuse intrasinusoidal metastatic carcinomaof the liver and to carcinomatous pulmonary embolism is included. The latter condition may be commoner and of greater clinical significance than his hitherto been appreciated. Some of the factors which may be responsible for this peculiar type of tumour dissemination are discussed.