RT Journal Article
SR Electronic
T1 The influence of paraproteinaemia on the Technicon automated platelet counter
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 583
OP 584
DO 10.1136/jcp.27.7.583
VO 27
IS 7
A1 Hall, P. C.
A1 Ibbotson, R. M.
YR 1974
UL http://jcp.bmj.com/content/27/7/583.abstract
AB In five patients whose serum contained a paraprotein it has been shown that platelet counts obtained using the Technicon AutoCounter are much too high. In two patients with IgG gammopathy the error is caused by some factor in the red cells lysed by the diluent solution 2M urea. In three patients with IgM gammopathy spurious platelet counts were produced by platelet-poor plasma when diluted with 2M urea. It is recommended that at the present time no patient known to have a paraprotein should have platelet counts performed on the AutoCounter.