TY - JOUR T1 - A renal biopsy study in toxaemia of pregnancy. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 681 LP - 692 DO - 10.1136/jcp.32.7.681 VL - 32 IS - 7 AU - C R Tribe AU - G E Smart AU - D R Davies AU - J C Mackenzie Y1 - 1979/07/01 UR - http://jcp.bmj.com/content/32/7/681.abstract N2 - Renal biopsy specimens from 11 women with severe pre-eclamptic toxaemia were examined by light and electron microscopy linked with immunofluorescence and immuno-electron microscopy. The part played by the mesangium in causing capillary loop thickening is stressed, and the progress of this 'strangulation' is illustrated. In contrast to the findings of most previous authors, IgM was demonstrated by direct immunofluorescence in all biopsy specimens, and its presence and site within the glomerulus were shown by immuno-electron microscopy in three cases. ER -