PT  - JOURNAL ARTICLE
AU  - C R Tribe
AU  - G E Smart
AU  - D R Davies
AU  - J C Mackenzie
TI  - A renal biopsy study in toxaemia of pregnancy.
AID  - 10.1136/jcp.32.7.681
DP  - 1979 Jul 01
TA  - Journal of Clinical Pathology
PG  - 681--692
VI  - 32
IP  - 7
4099  - http://jcp.bmj.com/content/32/7/681.short
4100  - http://jcp.bmj.com/content/32/7/681.full
SO  - J Clin Pathol1979 Jul 01; 32
AB  - Renal biopsy specimens from 11 women with severe pre-eclamptic toxaemia were examined by light and electron microscopy linked with immunofluorescence and immuno-electron microscopy. The part played by the mesangium in causing capillary loop thickening is stressed, and the progress of this 'strangulation' is illustrated. In contrast to the findings of most previous authors, IgM was demonstrated by direct immunofluorescence in all biopsy specimens, and its presence and site within the glomerulus were shown by immuno-electron microscopy in three cases.