RT Journal Article
SR Electronic
T1 A renal biopsy study in toxaemia of pregnancy.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 681
OP 692
DO 10.1136/jcp.32.7.681
VO 32
IS 7
A1 Tribe, C R
A1 Smart, G E
A1 Davies, D R
A1 Mackenzie, J C
YR 1979
UL http://jcp.bmj.com/content/32/7/681.abstract
AB Renal biopsy specimens from 11 women with severe pre-eclamptic toxaemia were examined by light and electron microscopy linked with immunofluorescence and immuno-electron microscopy. The part played by the mesangium in causing capillary loop thickening is stressed, and the progress of this 'strangulation' is illustrated. In contrast to the findings of most previous authors, IgM was demonstrated by direct immunofluorescence in all biopsy specimens, and its presence and site within the glomerulus were shown by immuno-electron microscopy in three cases.