RT Journal Article
SR Electronic
T1 Characteristics of Pseudomonas aeruginosa in relation to laboratory-induced resistance to gentamicin.
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 723
OP 727
DO 10.1136/jcp.32.7.723
VO 32
IS 7
A1 Dimitracopoulos, G
A1 Intzes, C
A1 Papavassiliou, J
YR 1979
UL http://jcp.bmj.com/content/32/7/723.abstract
AB Pseudomonas aeruginosa strain C2 was habituated to gentamicin by serial passage in broth containing increasing concentrations of the antibiotic and up to 250 microgram/ml. The resistant progenies differed from the parent strain in antibiotic susceptibility to two other aminoglycosides, colonial morphology, lytic phage patterns, phage adsorption, and agglutination with the seven Fisher's antisera. All the progenies failed to grow at 42 degrees C and oxidised glucose in O/F tubes after incubation at 37 degrees C for three days but were catalase- and oxidase-positive. Reversion to the original properties of the parent strain was demonstrated in all cases after 10 serial subcultures in antibiotic-free broth.