PT  - JOURNAL ARTICLE
AU  - Lauriola, L
AU  - Musiani, P
AU  - Carbone, A
AU  - Bartolini, M
AU  - Cianciulli, P
AU  - Piantelli, M
TI  - T-cell nature of leukaemic cells in a case of Sézary's syndrome with 'null-cell' features.
AID  - 10.1136/jcp.32.9.912
DP  - 1979 Sep 01
TA  - Journal of Clinical Pathology
PG  - 912--917
VI  - 32
IP  - 9
4099  - http://jcp.bmj.com/content/32/9/912.short
4100  - http://jcp.bmj.com/content/32/9/912.full
SO  - J Clin Pathol1979 Sep 01; 32
AB  - alpha-naphthyl acetate esterase (ANAE) activity has been investigated in leukaemic cells from peripheral blood in a typical small-cell Sézary syndrome (SS) case in which cerebriform mononuclear cells failed to form E rosettes. The 'dot-like' ANAE positivity found in the majority of these neoplastic cells strongly supports a T-cell origin. In addition, a non-monocytic, non-B-cell nature of Sézary cells is indicated by the lack of Ia-like antigens. Finally, there is evidence of a distinct portion of Sézary cells simultaneously expressing ANAE activity and Fc IgM receptors.