TY - JOUR T1 - Osteogenesis imperfecta (lethal) bones contain types III and V collagens. JF - Journal of Clinical Pathology JO - J Clin Pathol SP - 534 LP - 538 DO - 10.1136/jcp.33.6.534 VL - 33 IS - 6 AU - F M Pope AU - A C Nicholls AU - C Eggleton AU - P Narcissi AU - E N Hey AU - J M Parkin Y1 - 1980/06/01 UR - http://jcp.bmj.com/content/33/6/534.abstract N2 - Lethal osteogenesis imperfecta (OI-L) and normal fetal bones contain types I and V collagen with relatively more type V in OI-L bones. The latter, unlike normal fetal bone, also contain some type III collagen. Such altered collagen ratios could directly produce the bony fragility and radiotranslucency of OI-L bones. Since this is an inherited osteoporosis similar alterations in acquired osteoporoses are also possible. ER -