PT - JOURNAL ARTICLE AU - S H Tsung TI - Circulating CK-MB and CK-BB isoenzyme after gastrointestinal surgery. AID - 10.1136/jcp.35.2.200 DP - 1982 Feb 01 TA - Journal of Clinical Pathology PG - 200--203 VI - 35 IP - 2 4099 - http://jcp.bmj.com/content/35/2/200.short 4100 - http://jcp.bmj.com/content/35/2/200.full SO - J Clin Pathol1982 Feb 01; 35 AB - The effect of gastrointestinal surgery on serum creatine kinase activity was studied in 30 patients. The MB isoenzyme was demonstrated in sera of 30% of the patients and BB isoenzyme in 23%. MB content varied from 0.8 to 10.3% of the total creatine kinase activity, and the BB content from 0.6 to 18.4%. The CK-BB was probably of gastrointestinal origin, since gastrointestinal tract contains high CK activity with BB isoenzyme predominating. A cardiac origin for the observed serum CK-MB isoenzyme increase would seem the most likely, although no patients showed evidence of electrocardiographic changes. Increased CK-MB activity has been observed in myocardial ischaemia without infarction.