RT Journal Article SR Electronic T1 Elution of 111Indium from reticuloendothelial cells. JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 507 OP 509 DO 10.1136/jcp.35.5.507 VO 35 IS 5 A1 A M Peters A1 I Klonizakis A1 J P Lavender A1 S M Lewis YR 1982 UL http://jcp.bmj.com/content/35/5/507.abstract AB Measurement of isotope accumulation in an organ is often used to assess that organ's removal of blood cells labelled with the isotope. This technique is only valid if the isotope does not elute from the organ. Elution of 111In from the liver and spleen has been investigated in 14 subjects following intravenous injection of heat-damaged erythrocytes labelled with 111In. The elution rate from the spleen was found to be low, about 2% of the initial activity per day. The liver accumulated activity with respect to its initial uptake at a rate of about 5% per day. Bone marrow was not visualised except in two patients in whom it was identifiable in the initial scan.