PT - JOURNAL ARTICLE AU - Carrell, R W AU - Lehmann, H TI - Zinc acetate as a precipitant of unstable haemoglobins. AID - 10.1136/jcp.34.7.796 DP - 1981 Jul 01 TA - Journal of Clinical Pathology PG - 796--799 VI - 34 IP - 7 4099 - http://jcp.bmj.com/content/34/7/796.short 4100 - http://jcp.bmj.com/content/34/7/796.full SO - J Clin Pathol1981 Jul 01; 34 AB - Whereas the addition of four moles of zinc acetate to one of normal human haemoglobin at pH 7.4 results in a clear solution, addition to unstable haemoglobin results in precipitate formation. Within certain limits no false-positive results are obtained with methaemoglobin, and with fetal haemoglobin. With excess zinc, normal haemoglobin also precipitates, but this process is reversible and can be used for a rapid concentration of dilute solutions of normal haemoglobin.